Takayama Fumihiko has released NesterDC 5.0-pre3 . It features the following in this latest version.

-4 players support.
-backout “cutting MMC2/MMC4 support”.
-speedup (works near 60fps, without PUNCHOUT and ex-sound ROMs)

You can get the latest version at Takayama Famihiko’s website located here.

Thanks to Huma for the news!